penis enlargement

Role of Testosterone and Dihydrotestosterone in Gynecomastia

September 10, 2010

Researchers in México examined the role of testosterone and dihydrotestosterone in the development of spontaneous gynecomastia in adolescents. They compared a group with pubertal spontaneous gynecomastia (PSG) and healthy young volunteers (HYV) to test a possible hormonal mechanism of gynecomastia at puberty.

The PSG group had an average testosterone (T) to dihydrotestosterone (DHT) ratio of 5.0 to 15.4, while the HYV group had a lower T:DHT ratio of 0.42 to 2.224.

The results led the researchers to two possible conclusions:

  1. Spontaneous gynecomastia might be caused by an enzimatic block of 5α-reductase (blocking the conversion of T to DHT);
  2. A decrease in the T:DHT ratio might favor the estrogen action for breast enlargement (aromatization of T to estriadol.)

This research was published in Systems Biology in Reproductive Medicine and was available in the Archives of Andrology. Read the full abstract here.

Topical DHT cream can address both of these possible causes. By applying DHT directly to the chest, you increase your DHT levels and compensate for the 5α-reductase block. Also, administration of DHT can lower testosterone production to be more in balance with estriadol, preventing aromatization and unwanted breast growth.

What is Gynecomastia?

Gynecomastia is a common disease of the male breast where there is a benign glandular enlargement of that breast at some time in the males life. It usually consists of the appearance of a flat pad of glandular tissue beneath a nipple which becomes tender at the same time. The development may be unilateral or bilateral. Find out more about Gynecomastia and how to treat it with DHT.