DHT – Dihydrotestosterone

Dihydrotestosterone (DHT) is an androgen, synthesized primarily in the male prostate gland, testes, hair follicles, and adrenal glands by the enzyme 5a-reductase. DHT has an important role in optimizing your over-all health and performance via the central nervous system, increasing strength, fighting against stress, and improving sexual function and libido.

Does DHT Cream Really Work for Penis Enlargement?

June 24, 2010

Andractim Penis GrowthWhen it comes to increasing penis size using Andractim DHT gel there’s one scientific study in particular that’s cited: Transdermal dihydrotestosterone therapy and its effects on patients with microphallus.

To investigate the efficacy of transdermal dihydrotestosterone therapy on 22 patients with microphallus, we applied dihydrotestosterone gel for 8 weeks to the external genitalia at daily doses of 12.5 mg. and 25 mg. for ages less than and older than 10 years, respectively.

All patients demonstrated growth of the penis during treatment. The mean increase rate (153%) in the first 4 weeks of treatment was higher than that (118%) of the second 4 weeks. Of importance is that responses were noted in 4 patients who had failed testosterone therapy for microphallus.

In conclusion, transdermal dihydrotestosterone therapy is an effective and relatively safe modality in the treatment of microphallus. (Source)

The key to DHT lengthening the penis lies in the number of active androgen receptors in the penis. By the time most men reach adulthood, the number of active androgen receptors has decreased dramatically, but they usually don’t disappear completely. Those that remain are sensitive to testosterone stimulation and may respond to PE programs that include DHT gel and penile ballooning. (According to research, penile growth cessation is controlled by mechanisms other than down regulation of androgen receptors.) With ballooning, penile tissues are literally soaked in DHT-enriched blood. Maintained for 30-60 minutes, this can stimulate the growth of new DHT receptors in the penis’ spongy tisssues. Increasing the DHT receptors in your penis will enable you to lengthen your penis with topical DHT cream.

DHT Cream for Penis Enlargement

June 18, 2010

DHT Cream for Penis GrowthDHT, or Dihydrotestosterone, is the hormone that causes the  spongy tissue in the penis (sinusoids) to get erect, repair and even grow.  Good penile blood circulation and human Growth Hormone (hGH) are also required for repair and penis growth. The most significant amount of penis growth happens during puberty, when DHT and hGH reach peak levels.

This helps explain why DHT/5-alpha reductase inhibitors  like Finasteride and Proscar eventually thin the tunica albuginea and depress sinusoids, eventually causing penile shrinkage with long-term use.

Teenage boys have a maximum penis size when their DHT levels peak. As they age and enter mid-life, DHT levels drop and the penis starts to shrink.

How Does DHT Cause Penis Growth?

The amount of DHT that your body produces and the effectiveness of your DHT hormone receptors are the two main ingredients of penis size.

When topically applied the penis, DHT will increase the number of penile cells, which in turn increases the amount of penile tissue that holds blood, lengthening the penis.

Applied daily in doses totaling up to 70mg, DHT should result in harder erections and an increased sex drive—often within days. DHT for penis enlargement should be cycled, so when you stop noticing these changes, stop using the DHT for 14-21 days, then start the cycle again. Most men experience the majority of penis growth from DHT in the first 6-8 weeks of treatment (longer, if properly cycled.)

Topical DHT cream is available online as Andractim DHT Gel.

DHT and Prostate Health

May 28, 2010

DHT and Prostate HealthDHT often gets a bad rap. It’s blamed for hair loss in men and women, as well as prostate growth. However, scientists are challenging some of these assumptions with research into DHT and benign prostate hypertrophy (BPH.) Some studies have suggested that higher estrogen levels are a cause of BPH. This has some researchers thinking that DHT–which cannot be converted to estrogen–could actually be used to treat BPH, and have filed a patent on their research.

Dihydrotestosterone for use in androgenotherapy
United States Patent 5648350

The present invention is directed to the administration of dihydrotestosterone (DHT) for preventing prostate cancer in male patients more than 50 years old and of reducing levels of plasma-borne sex hormone binding globulins (SHBG) in male patients having elevated levels thereof.

A short-term study with an aromatase inhibitor in men suffering from BPH has shown a mean reduction of 26% of the prostate volume, which reinforces the hypothesis of the responsibility, also for men, of certain estrogens. Not only does the activity of aromarase tend to increase with age, but experience suggests a slight tendency toward less sensitivity of the prostate cells to DHT with age, and on the contrary, toward a greater sensitivity to estradiol.

Read the full patent application here.

The research uses a 2.5% DHT hydroalcoholic gel (Andractim.)

The Advantage of DHT for Androgen Replacement

May 15, 2010

DHT for Androgen ReplacementTestosterone therapy is commonly used to treat male hypogonadism and androgen deficiency. Dihydrotestosterone (DHT) is a potent androgen that cannot be aromatized to Estriadol, and is therefore a “pure androgen.”

A potential advantage of DHT over Testosterone as an androgen replacement therapy is the reported muted effects of DHT on prostate growth. The potential beneficial effect of less prostate growth after DHT requires substantiation but, if true, highlights the advantage of using a pure androgen over an aromatizable androgen for hormone replacement.

Read the full abstract here.

DHT Lowers Cholesterol

April 20, 2010

DHT Reduces CholesterolWhile researching whether dihydrotestosterone (DHT) alone has an inhibiting effect on pituitary luteinizing hormone (LH) secretion, researchers discovered that 3 months of transdermal DHT cream resulted in lowered cholesterol. More specifically, they noted a moderate decrease in plasma cholesterol and low-density lipoprotein (LDL) levels, and a slight decrease in high-density lipoprotein (HDL)-cholesterol levels. This suggests that topical DHT gel is relatively safe for androgen replacement therapy as far as atherogenicity is concerned.

Read the full abstract here.

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